An A1C (glucose level in the blood) measurement of 7 percent or lower is ideal for most people with Type 2 diabetes. In one study with 1,262 patients who took Januvia for 18 weeks or 24 weeks, researchers found 100 mg daily lowered A1C by 0.7 percent and 0.8 percent respectively. Januvia and Janumet are prescription drugs that belong to a group of Type 2 diabetes drugs called incretin therapies. These drugs work by signaling the pancreas to create more insulin and decreasing the sugar made by the liver. You should talk with your doctor about any side effects you’re having.
Januvia and other medications
The dosages in this article are typical dosages provided by the drug manufacturer. If your doctor recommends Januvia for you, they will prescribe the dosage that’s right for you. Always follow the dosage that your doctor prescribes for you. To help make sure that you don’t miss a dose, try using a medication reminder. This can include setting an alarm or timer on your phone or downloading a reminder app. Be sure to check your blood sugar according to your doctor’s instructions while taking Januvia.
What are the serious side effects of Januvia
Pain in your joints is a possible side effect of taking Januvia. Joint pain is also a side effect of diabetes drugs that are similar to Januvia. More studies are needed to know the specific risk of having joint pain while taking Januvia.
- In a randomized, placebo-controlled crossover study, 79 healthy subjects were administered a single oral dose of sitagliptin 100 mg, sitagliptin 800 mg (8 times the recommended dose), and placebo.
- To learn more about Januvia, see this in-depth article.
- Researchers suggest keeping Januvia doses at less than 100 milligrams (mg).
- In one study with 1,262 patients who took Januvia for 18 weeks or 24 weeks, researchers found 100 mg daily lowered A1C by 0.7 percent and 0.8 percent respectively.
- Like Januvia, the proper functioning kidneys are necessary to filter Janumet out of the body.
FDA Drug Information
A return to baseline levels of renal impairment has been observed with supportive treatment and discontinuation of potentially causative agents. Consideration can be given to cautiously reinitiating JANUVIA if another etiology is deemed likely to have precipitated the acute worsening of renal function. Advise patients of the characteristic symptoms of heart failure and to immediately report such symptoms. If heart failure develops, evaluate and manage according to current standards of care and consider discontinuation of JANUVIA. Do not take JANUVIA if you are allergic to any of its ingredients, including sitagliptin.
What happens if I miss a dose?
More studies are needed to confirm the effects of blood sugar levels on hair loss. DPP-4 is a protein that blocks the action of incretin hormones. When you eat a meal, your digestive tract releases incretins. They affect your pancreas, stimulating it to make and release insulin.
All the drugs mentioned here treat type 2 diabetes, but they don’t treat type 1 diabetes. If you have kidney problems, you might need renal dosing of Januvia. Renal dosing is typically a lower dose than usual, such as 50 mg or 25 mg per day. The recommended dosage of Januvia for type 2 diabetes is 100 mg once per day.
To learn more about side effects of Januvia, check out this article. This medication is a type of dipeptidyl peptidase-4 (DPP-4) inhibitor. You may be able to take advantage of prescription savings on JANUVIA.
Januvia is only part of a complete treatment program that may also include diet, exercise, weight control, blood sugar testing, and special medical care. “Government price controls decimate the innovation ecosystem that continues advancing global human health.” Januvia and Janumet come in a variety of selling prescription drugs illegally dosages, depending on each individual’s needs for glucose control. These drugs are not meant to treat people with Type 1 diabetes. People who have excess toxins known as ketones in the blood or urine — a life-threatening condition known as diabetic ketoacidosis — should not take Januvia or Janumet.
But do not stop taking the drug without first talking with your doctor. Here’s a short list of some of the mild side effects that Januvia can cause. To learn about other mild side effects, talk with your doctor or pharmacist, or read Januvia’s prescribing adderall xr amphetamine dextroamphetamine mixed salts information. Your doctor or pharmacist can tell you more about the potential side effects of Januvia. They can also suggest ways to help reduce side effects. However, as with all drugs , there are side effects and you should discuss with your doctor.
These hormones are rapidly inactivated by the enzyme, DPP-4. The incretins are part of an endogenous system involved in the physiologic regulation of glucose homeostasis. When blood glucose concentrations are normal or elevated, GLP-1 and GIP increase insulin synthesis and release from pancreatic beta cells by intracellular signaling pathways involving cyclic AMP.
In the study of JANUVIA as initial therapy with pioglitazone, one patient taking JANUVIA experienced a severe episode of hypoglycemia. There were no severe hypoglycemia episodes reported in other studies except in the study involving coadministration with insulin. Kidney problems may increase how much Januvia stays in your body. This can lead to complications, including pain or pressure in your chest or swelling of your legs, ankles, and feet. Rarely, some people reported kidney problems or kidney failure after taking Januvia. Januvia is only approved to treat high blood sugar caused by type 2 diabetes.
All drugs have side effects and come with some level of risk. However, the risk from untreated type 2 diabetes can also adversely impact your health. Left untreated, type 2 diabetes medications for alcohol use disorders can cause serious medical problems such as nerve and kidney damage, vision problems, and heart disease. Januvia may cause inflammation of the pancreas, which is called pancreatitis.